Symposium — Monday, April 24, 2017 — 3:15 PM - 5:15 PM — , Room W196A
Respiration Section — Chair: Wolfgang M. Kuebler — Co-Chair: Eleftheria Letsiou
Over recent years, lipid mediators have become recognized as a central and ubiquitous group of signaling molecules that regulate a broad palette of cellular functions and responses including cell death, proliferation, differentiation, contraction, ion channel activity, to name a few. Lipid mediators such as resolvins, sphingolipids, or lysophosphatidic acid are increasingly recognized as important regulators of lung functions in health in disease. This symposium will highlight the critical roles of lipid mediators in four major lung diseases: asthma, acute lung injury, pulmonary hypertension, and lung fibrosis. The presentations will cover novel signaling roles of lipids and mechanisms of disease, and will also discuss translational and clinical data that demonstrate the relevance of these signaling pathways for human disease.