Flex Session — Wednesday, April 26, 2017 — 2:30 PM - 4:30 PM — , Room W196C
Translational Physiology Interest Group — Chair: Prachi Singh — Co-Chair: Paul Cohen
Obesity increases the risk of several serious health conditions ranging from cardiovascular disease, diabetes, NASH, and cancer. Increased leptin is recognized to be partly responsible for these associations in obesity. However, most studies investigating the roles of leptin are correlational, and are largely focused on the central role of leptin in energy homeostasis. The direct role of leptin in peripheral tissues is largely unappreciated. Recent advances in leptin research have indicated that leptin may be targeted to prevent and treat obesity related disease conditions. However, to explore the therapeutic potential of leptin, it is important to understand the contribution of leptin to complete human pathophysiology. The symposium includes experts with diverse research interests allowing the audience to appreciate the importance of leptin to human physiology beyond its central role in appetite suppression. This session encourages interaction between different disciplines helping to conjure the potential translational implications of leptin to human health.