Flex Session — Wednesday, April 26, 2017 — 2:30 PM - 4:30 PM — , Room W196A
Translational Physiology Interest Group — Chair: Petra Kleinbongard — Co-Chair: Karima Ait-Aissa
Vascular homeostasis is highly dependent connected the genetic and environmental modifiers which can change or inhibit mechanism of vasodilation. The study of animal models has brought great insights into these complex pedigrees of vascular signaling, but in order to facilitate clinical applications further evidence in human studies needs to be gathered. There are a number of factors released from the endothelium, circulation or surrounding matrix. A high degree of redundancy exists in this regulation which may have important implications for blood flow in disease. In this symposium, mechanisms of dilation in health and disease will be presented. The role of role of the mitochondria and its importance in producing vasodilators from the endothelium will be presented. Better understanding the mechanism of vasodilation in health and disease could profoundly impact our knowledge regarding vascular pathology including atherosclerosis, hypertension and endothelial dysfunction. The goal of this symposium is to present cutting edge innovative research in vascular physiology that will be both provocative and educational.