Single Cell Analysis and Genomic Approaches

Symposium — Sunday, April 23, 2024 — 3:15 PM - 5:15 PM — , Room W194B
Physiological Genomics Group — Chair: Hilary Coller — Co-Chair:

The capacity to analyze data from single cells has changed our understanding of biology and made us realize that individual cells within a population can vary greatly for any given parameter.  This intercellular heterogeneity is easily missed by experiments that only analyze cellular pools.  The heterogeneity of cells can, in some cases, be a critical driver for our understanding of the biological behavior of the population. This symposium will discuss methods for single cell analysis and the latest findings using these approaches in a variety of model systems.

Speakers

• Introduction/Overview
  Hilary Coller — , UCLA


• Cellular Variability and Information Flow in Signal Transduction Networks
  Roy Wollman — Department of Chemistry and Biochemistry, University of California, San Diego


• Defining Cell Types and States with Single-Cell Genomics
  Cole Trapnell — Foege S-333C, University of Washington


• Understanding Reprogramming of Somatic Cells to Pluripotency at the Single Cell Level
  Kathrin Plath — 615 Charles E Young Drive South, UCLA


• Single Complexity: Multiple-Omics from Single Cells
  Jim Eberwine — , University of Pennsylvania


• Conclusion.
  Hilary Coller — Biological Chemistry, University of California, Los Angeles