Autophagy: driver of microbiome composition and intestinal homeostasis

Featured Topic — Tuesday, April 25, 2024 — 8:00 AM - 10:00 AM — , Room W194B
GI and Liver Physiology Section — Chair: Arianne L Theiss — Co-Chair:

Autophagy is an evolutionarily conserved catabolic pathway that removes cytoplasmic components through lysosomal degradation. Autophagy promotes cell survival and restores cell homeostasis in response to cellular stressors such as starvation, damaged organelles, or the invasion of microorganisms. The mechanisms by which autophagy contributes to intestinal homeostasis will be discussed, focusing on its cell type-specific roles in regulating gut pathogens clearance, innate immunity, and inflammation. 

Speakers

• Autophagy and ER stress in the pathogenesis of inflammatory bowel diseases
  Richard S Blumberg — Harvard Digestive Diseases Center, Brigham and Women's Hospital