Omics approaches to understanding muscle biology

Flex Session — Wednesday, April 26, 2024 — 2:30 PM - 4:30 PM — , Room W194B
Cell and Molecular Physiology Section — Chair: Jatin George Burniston — Co-Chair: Yi-Wen Chen

The aim of this symposium is to educate and inform delegates of the principles and latest practices of -omic research applied to skeletal muscle. Omic sciences can be sub-divided based on the level of biological organization/ macromolecule i.e. genomics (DNA), transcriptomics (RNA), proteomics (protein), and metabolomics (metabolite). We have selected speakers to represent each of these sub-disciplines, and skeletal muscle will be our second unifying theme. Major areas of focus in skeletal muscle research include developmental biology, muscular dystrophies, exercise, insulin resistance and atrophy due to disuse, aging or disease. This symposium will highlight the latest research relevant to these areas and, specifically, the talks will highlight new findings in myogenesis, type 2 diabetes, and the response to exercise training.

Speakers

• DamID profiling during myogenesis defines heterochromatin flux at the nuclear envelop
  Jelena Perovanovic — , National Institues of Health, Bethesda


• Beyond timekeeping, the transcriptional landscape of the molecular clock in skeletal muscle
  Karyn A Esser — Department of Physiology and Functional Genomics, University of Florida


• Proteomics insights in to insulin resistance in muscle
  Lawrence Mandarino — , Mayo Clinic


• Metabolomics and fluxomics reveal pathways underlying enhanced muscle performance in exercise
  Charles Burant — , University of Michigan Medical School