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Mechanotransduction in Cardiovascular Function

Featured Topic — Wednesday, April 25, 2024 — 1:30 PM - 3:00 PM — Convention Center, Room 26
Cardiovascular Section — Chair: Charles Thodeti — Co-Chair: Sarah Lindsey

This featured topic will cover mechanical signaling in cardiovascular cell function. Topics include endothelial, smooth muscle, cardiac fibroblast and cardiomyocyte mechanisms in both health and disease. The cardiovascular system is highly mechanically active, and the majority of cells in the cardiovascular system are exposed to mechanical forces which regulate various cardiovascular functions such as vascular growth, arterial stiffness and cardiac remodeling. However, the mechanical signaling mechanisms in cardiovascular function is not well known as most of the studies are focused on the role of soluble growth factors. Therefore, we propose to have a featured topic on this important but ignored area of research. We will select speakers from the abstracts submitted and believe this featured topic will serve as platform for disseminating latest results from mechanical signaling in cardiovascular function and ignite new interests in scientists across CV section.

Speakers

  • TBD.
    TBD —

  • Two N-glycosylated Asparagines within Endothelial αENaC are Crucial for Shear Force Sensing and Blood Pressure Regulation in vivo
    Fenja Knoepp — Justus-Liebig-University of Giessen

  • Glypican-1 Mediates Endothelial Hyper-permeability in a Model of Acute Heart Failure
    Andreia Chignalia — University of Illinois at Chicago

  • TRPV4 channel deletion or pharmacological inhibition protects heart against adverse remodeling post-myocardial infarction
    Ravi kumar Adapala — Northeast Ohio Medical University

  • Type 2 Diabetic Coronary Vascular Smooth Muscle Cells Exhibit Decreased Stiffness and Decreased Adhesion
    Patricia McCallinhart — Nationwide Children's Hospital

  • Laminin-β6 integrin Interaction is Crucial for Coronary Collateral Growth
    Gregory Joseph — New York Medical College

  • Effects of Exercise-Induced Shear Stress on Endothelial Gene Expression
    Francisco Morales-Acuna — The University of Texas at El Paso

  • CHAIR
    Charles Thodeti —

  • COCHAIR
    Sarah Lindsey —





 

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