Sympathetic Neurovascular Transduction in Humans: Are We There Yet?
Symposium — Tuesday, April 24, 2024 — 1:30 PM - 3:00 PM — Convention Center, Room 28B
Neural Control and Autonomic Regulation Section — Chair: J. Kevin Shoemaker — Co-Chair:
The concept of neurovascular transduction
depicts a fundamental physiological mechanism in organ function and
cardiovascular stability. Thus, this concept remains critically important to understanding
basic physiology and clinical problems.
We know that sympathetic neurovascular transduction occurs. However, the
complexity of co-transmitter release, patterns of postganglionic recruitment,
competing dilatory and constrictor signals in the neuro-vascular complex, and
inability to directly visualize the process in each organ, complicate the
process of understanding neurovascular interactions. Thus, despite its
important role in overall physiology, important barriers exist even in the quantification
of this process. This symposia will present the most recent advances in methods
used to study and quantify neurovascular transduction, ranging from signal
processing of human nerve recruitment and nerve-blood flow interactions in
intact human and experimental microvascular levels, to optogenetic models in
conscious rodent preparations.
Speakers
- Neurovascular transduction in humans: New approaches to old questions.
Can Ozan Tan — Cognitive and Neural Systems, Harvard Medical School
- Sympathetic transduction: Implications for health and disease.
Paul Fadel — Center for Research and Scholarship, University of Texas at Arlington
- From one generation to the next: differential distribution of sympathetic receptors in skeletal muscle microvasculature.
Baraa Al-Khazraji — Kinesiology, Western University
- CHAIR
Kevin Shoemaker —
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