Renal Section Young Investigator Award Featured Topic: Novel Roles for Renal GPCRs

Featured Topic — Sunday, April 22, 2024 — 8:30 AM - 10:00 AM — Convention Center, Room 28A
Renal Section — Chair: Jennifer Pluznick — Co-Chair: Michael Caplan

It has long been appreciated that G-protein coupled receptors (GPCRs) play pivotal roles in renal physiology.  However, in recent years studies have begun to examine 'novel' GPCRs, i.e., receptors which have not previously been studied in the kidney.  Consequently, new and unexpected roles have emerged for renal GPCRs, yielding new insights into kidney function in health and disease.  This Featured Topic will highlight findings examining novel roles for GPCRs in the kidney.

Speakers

• Orphan GPCRs and renal physiology.
  Jennifer Pluznick — Physiology, Johns Hopkins School of Medicine


• Activation of G Protein-coupled Estrogen Receptor Promotes Endothelin-dependent Natriuresis in Female Rats
  Eman Y Gohar — University of Alabama at Birmingham


• Deep Proteomic Quantification of Inner Medullary Collecting Duct Protein Phosphorylation: Response to Vasopressin
  Venkatesh Deshpande — NHLBI


• Kir4.1 is involved in Bradykinin-induced inhibition of NCC and natriuresis
  Peng Wu — New York Medical College


• Intrarenal Bradykinin (BK) is Decreased in Mice with Prorenin Receptor (PRR) Deficiency in the Collecting Duct
  Bruna Visniauskas — Tulane University


• Renal Olfactory Receptor 1393 Contributes to the Progression of Diabetes
  Blythe D Shepard — Georgetown University


• Genetic Deletion of P2Y2 Receptor Suppresses Lithium-induced Medullary Collecting Duct Remodeling in Mice
  Bellamkonda K Kishore — Univ. of Utah & VA Med Ctr


• COCHAIR
  Michael Caplan —